This is really good input Gabriel! Keep it coming!
I experiment a lot with various supplements/vitamins/minerals, but I don't experiment with drugs. I haven't tried Ipriflavon or perhexiline maleate--are those drugs? If you're interested in using drugs to improve your apnea, I can list a zillion which I have come across in journals (i.e. phenytoin)
Concerning the other substances (vitamin E, malic acid, magnesium, germanium), I have tried them. Unfortunately, when I experiment on myself, I can never make a completely controlled experiment. It can take quite a while for a particular supplement to show a statistical benefit, when I review the journals in which I record all my experiments. As you have shown with your quotes, I believe that the above four agents could help apnea, but magnesium has not helped me, I find that supplementing magnesium without calcium throws off my electrolyte balance. Vitamine E, malic acid, and germanium may show minor effects; certainly vitamin E, when taken in ENORMOUS doses, has shown huge capacity to improve survival rate of rats in extreme hypoxia, but vitamin E is fat soluble and if you take such big doses you'll rapidly accumulate too much in your body, eliminating its usefulness as a 'chronic' aid for apnea. I need to experiment more with Vitamin E/malic acid/germanium (as well as a huge list of others) before I can really comment on whether they help or not; the fact that I can't really tell yet means that the effect can't be that big.
Certain supplements and/or foods have good and bad effects. Take garlic for example. Raw garlic was eaten in excess by the polynesian pearl divers to increase breath-hold times. Does it work? In a sense yes; it increases your capacity to hold your breath, but it also increases the likelihood of a blackout. Garlic has tons of active compounds, including allicin, methyl-allyl-trisulfide, L-arginine, adenosine, and a small amount of organic germanium. It definitely vasodilates all your blood vessels, and it inhibits hypoxia induced pulmonary vasoconstriction. Allicin, L-arginine and methyl-allyl-trisulfide ALL act as vasodilators in different ways, and allicin also acts as an anti-bacterial compound similar to penicillin, hence the old practice of eating garlic to ward off illness. However, the vasodilation effect reduces your blood pressure so much that you tend to black out earlier than before...
In my experiments, there are only a couple of foods/supplements which have shown a massive, instant, repeatable effect. Keep guessing Gabriel; maybe you'll hit them!
Eric Fattah
BC, Canada
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