[naiad]

So more HCO3 buffers means less dissolved CO2, therefore less lowering of pH, therefore less Bohr effect? Maybe having good CO2 tolerance (more buffers) means that hyperventilation will have a greater effect on O2 availability?

I don't do heavy hyperventilation, and I hardly ever breathe up for more than 2min. This works best for me. My CO2 tolerance is normally quite good, and very good if I have done lots of tables.