Erika Schagatay : static apnoea
The spleen of diving mammals is an extra storage site for erythrocytes when
they are not needed for oxygen delivery.
This supply can be ejected into the circulation during diving to temporarily
enhance gas storage. This effect is also present in mammals specialized in
endurance running, eg, horses & dogs, and also in humans during intense
exercise. The purpose of the storage is likely reduction of blood viscosity
between these periods of activity. Splenic contraction in humans during
apnoea diving was first observed in Ama divers. The resulting Hb increase
is associated with an increased apnoeic duration, which is not present in
splenectomized subjects.
It was recently observed that the best performances in competitive apnoeic
diving were associated with the largest spleens, with volumes of up to 600
ml. The difference in splenic contraction between the smallest versus the
largest spleens measured in the elite divers was equivalent to an increase
of apnoeic duration by 30 seconds (unpublished observations). It is still
unclear if this represents genetic diversity and pre-selection or
training-induced changes, but the observed growth of a small accessory
spleen after removal of the main spleen suggests a high regenerative
ability. The Hb elevation during apnoea is greater in divers than in
untrained subjects and endurance athletes, suggesting a training-induced
promotion of the response.
Splenic contraction has been shown to be an active contractile process. It
is at least partly induced by hypoxia. It was originally suggested to be
part of the human diving response, but it now seems that it is not linked to
the cardio-vascular response, as the two responses are not induced by the
same stimuli and occur on separate time scales. Splenic contraction
develops progressively across an apnoea and may need several apnoeas to
develop fully (Figure 3).
> E Schagatay 2009 Diving and Hyperbaric Medicine 3:88-99
> Predicting performance in competitive apnoea diving
> Part I: static apnoea
>
> Ever since the first deep diving competitions were organized, there has been
> debate about when the ultimate limits of human apnoeic performance will be
> reached, and which factors will determine these limits.
> Divers have thus far surpassed all former predictions by physiologists in
> depth and time.
> The common factor for all competitive apnoea disciplines is apnoeic
> duration, which can be prolonged by any means that increase total gas
> storage or tolerance to asphyxia, or reduce metabolic rate.
> These main factors can be broken down further into several physiological or
> psychophysiological factors, which are identified in this review.
> Like in other sports, the main aim in competitive apnoea is to extend human
> performance beyond the known limits.
> While a beginner may extend apnoeic duration by getting closer to his or her
> personal limit, the elite diver can only extend the duration further by
> pushing the individual physiological limit further by training.
> In order to achieve this, it is essential to identify the performance
> predicting factors of apnoea sports and which factors can be affected by
> training, work that has only just begun.
>
> This is the first of two papers reviewing the main factors predicting
> performance in competitive apnoea diving, which focuses on static apnoea,
> while the following paper will review dynamic distance and depth
> disciplines.
> Great improvements have been made in all diving disciplines in recent years
> and the 10-minute barrier in resting 'static apnoea' has been broached.
> Despite this, current training methods and the strategies employed suggest
> that duration can be prolonged still further, and divers themselves suggest
> the ultimate limit will be 15 minutes, which appears physiologically
> possible, for example, with further development of techniques to reduce
> metabolic rate.
Also, bone from blood: how mineral salts are carried in blood to accumulate in collagen matrix to form bone, and how it can be recycled back into the blood for use elsewhere, and its relation to white blood cells.
http://www.eurekalert.org/pub_releases/2009-07/uops-bfb072309.php