I think the bad news is in.

[Sorandril]

https://www.tandfonline.com/doi/abs/10.1080/02699052.2016.1179792

Amyloid-beta peptide and phosphorylated tau in the frontopolar cerebral cortex and in the cerebellum of toothed whales: aging versus hypoxia

Summary: Immunohistochemical analysis showed positive immunolabeling for amyloid-beta peptide and phosphorylated tau in the cerebral and cerebellar cortex of toothed whales. These findings could be linked to hypoxic phenomena.

bio.biologists.org

And much like the Wu Tang Clan, amyloid beta ain’t nothing to f—- with.

I think we all need to quit now to save our brains, Stig included.

 

[Sorandril]

https://www.cell.com/neuron/fulltext/S0896-6273(03)00367-2?code=cell-site&mobileUi=

Of course there’s this stuff HIF is doing but I doubt it’s enough.

 

[Sorandril]

https://scholar.google.com/scholar?hl=en&as_sdt=0%2C44&q=Alzheimer%E2%80%99s+diving&btnG=#d=gs_qabs&u=%23p%3D8JQfFz0SjZkJ

Well at least there’s some good news about s100.

 

[Sorandril]

RETRACTED: Intermittent Hypoxia-Hyperoxia Training Improves Cognitive Function and Decreases Circulating Biomarkers of Alzheimer’s Disease in Patients with Mild Cognitive Impairment: A Pilot Study

Alzheimer’s disease (AD) affects not only the central nervous system, but also peripheral blood cells including neutrophils and platelets, which actively participate in pathogenesis of AD through a vicious cycle between platelets aggregation and production of excessive amyloid beta (Aβ)...

www.mdpi.com

And then there’s this. I’ll stop now.
Edit to note that this was a terrible morning. However I will add that those markers are also increased by SCUBA without benefits of HIF.

seems to be a dcs problem

also, exercise: https://www.researchgate.net/profil...through-modulating-mitochondrial-dynamics.pdf

I’m looking forward to discussing the data and perhaps launching a study on alz and diving.

 

[Lil Dragonfly]

Curcumin and beta-amyloid:

https://www.ncbi.nlm.nih.gov/pmc/ar...research on amyloid-β,and amyloid-β in humans

https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-018-0577-2

Is it ok for me to post ancedotal evidence that this stuff works, or is this subforum for formal studies only?

 

[7BDiver]

I do not see that these studies are any less substantial than most all studies within ncbi, there are always follow up studies needed to find irrefutable evidence. It wold be interesting to see which cultures have greater Curcumin absorption due to food preparation as bio availability is limited by solubility. It was discussed Curcumin was commonplace in Asian food and statistics would show Africa, India, and South Asia have the lowest AD occurrence by demographic.

 

[Lil Dragonfly]

I do not see that these studies are any less substantial than most all studies within ncbi, there are always follow up studies needed to find irrefutable evidence.

To clarify- by "anecdotal evidence" I was NOT referring to the links I posted, I was asking for permission to write about informal experiments I did on myself (without any doctors or researchers involved). I am not sure if DB is the right audience or not for that sort of thing.

 

[Lil Dragonfly]

Gah. Still learning how to quote :/

How do I fix my previous post?

 

[7BDiver]

It's all fair game, any enlightening and educational information based on personal experience or professional studies is appreciated. There has certainly been some wild and even adult audience ideas expressed in the forum. Freediving science involves much of our physiology and psychology with plenty more to explore and understand, it's what makes it the greatest.

 

[Lil Dragonfly]

It's all fair game, any enlightening and educational information based on personal experience or professional studies is appreciated.

I became confused. My mannerisms resembled the mannerisms of one of my friends (both of his parents had Alzheimers). And I could feel sticky junk covering my brain (unlike most people, I am able to feel my internal organs. My family had to explain to me that most people cannot. Perhaps this is an autism trait?)

So I did some Googling, and found out that curcumin/turmeric removes beta-amyloid from the body. I then combined:

1. Either turmeric or Jarrow curcumin (forget which one)
2. High dose Jarrow MSM (polyphenols and terpenes deplete sulfur)
3. Jarrow milk thistle (elevates glutathione)

Afterwards I felt funny. Then, when I went to the bathroom this sticky junk came out in my stools.

Then I returned to feeling normal.

There has certainly been some wild and even adult audience ideas expressed in the forum.

Sending you a PM.

 

[7BDiver]

That is quite an unusual experience and attribute that allowed you to find a resolution to a health problem that most would not be able to even perceive. I wonder if you have a particularly strong Brain-Gut connection which has significant health importance for the brain, this an area of study gaining great attention lately. How significant is the perception of your organs in diving?

 

[ReefTroll]

I’m not seeing the actual issue here?

I became confused. My mannerisms resembled the mannerisms of one of my friends (both of his parents had Alzheimers). And I could feel sticky junk covering my brain (unlike most people, I am able to feel my internal organs. My family had to explain to me that most people cannot. Perhaps this is an autism trait?)

So I did some Googling, and found out that curcumin/turmeric removes beta-amyloid from the body. I then combined:

1. Either turmeric or Jarrow curcumin (forget which one)
2. High dose Jarrow MSM (polyphenols and terpenes deplete sulfur)
3. Jarrow milk thistle (elevates glutathione)

Afterwards I felt funny. Then, when I went to the bathroom this sticky junk came out in my stools.

Then I returned to feeling normal.



Sending you a PM.

basically your concoction was made up from three things that have been shown clinically with a potential to cause diarrhoea.
As for curcumin being able to provide health benefits 100’s if trials have been done and it was shown to be useless

 

[7BDiver]

Curcumin is in the the very least known as an anti-inflammatory component of the spice turmeric, this is a significant medicinal property.

 

[ReefTroll]

Curcumin is in the the very least known as an anti-inflammatory component of the spice turmeric, this is a significant medicinal property.

To get enough curcumin from turmeric you’d need to eat enough to be able to bury a child in it. Even then curcumin is subject to poor bioavailability and ingesting it alone renders almost zero benefits. So is it really useful/effective to say it is worthwhile? Would you bother taking a version of paracetamol if it had low levels of effectiveness and required other items? No, we’d look at it for what it is, a low level product in terms of effectiveness.