Yes, I am looking into dissolvable filaments, too. Not to be used as supports but to make whole parts out of and then do the composite layup on top of the part. But I'd ideally want the filament to fulfill three criteria; it should be dissolvable in water or a chemical that is not too harsh and one that does not harm the epoxy, it should be fairly stiff so that can vacuum bag it and finally it would be amazing if it would still hold up nicely at about 70C (then you could do prepreg or post curing laminates). Most PVA is pretty soft and has a low TG but the filaments which are stiffer are difficult to dissolve... Anyways, I will keep looking and I have a feeling that in a year or two, we will have something worthwhile on hobby level.
Now, I did three quick test prints of my nylon samples from eSun. From left to right they are their regular unfilled nylon - eSun call it ePA (I am not sure which type of nylon is it but possibly PA6), in the middle is a glass fiber filled one called ePA-GF and the last one is their ePA-CF which is carbon fiber reinforced:
The "pure" nylon one is a bit ductile, the glass fiber one is a lot stiffer and the CF is possibly even slightly stiffer.
I don't think I will be using the pure version as it doesn't machine well, also it is trickier to print. The fibers in the two others seem to really help both the printability and machinability and I think the surface left from machining is just about smooth enough to obtain a seal on.
Though the fiber filled ones behave better on the printer, they are still not super easy to print. E.g. the darker band on the glass fiber part about 2/3rds up is just from turning the fan off vs. running it at 30% during printing. It is possibly better fused, definitely more smooth but also the diameter of the part in that area is at least 0.2mm different from the rest.
PLA is a lot less fussy to print well. So, if you need dimensionally correct parts, I think you would definitely need to spend quite a bit of time running calibration tests for this particular filament until you got something controllable and repeatable.
I also gave the three parts an hour in the oven at 80C - I think this is an OK test for a part left in the sun (remember, it was the low TG of PLA that led me onto nylon in the first place):
Again, the purer one was quite soft straight out of the oven, the glass fiber one a lot less soft and the CF was the stiffest of the three.
The main issue with nylon is that it absorbs water and the water changes its characteristics, e.g. making it softer and increase in size. This takes a few days, I guess but I know that sometimes injection molding companies drop brand new parts in boiling water to speed up the process before sending the parts to the customer. That way, the part dimensions don't change between leaving the factory and being checked at the customer.
So, I dropped my three testers in a pot of boiling water, too. And while they did absorb water and become softer to the touch, I think I will let them sit overnight to reach some sort of equilibrium before making any conclusions on that point.